Wednesday, September 21, 2005

More on the EU Stem Cell Research Project

More on the EU Stem Cell Research Project

The German website fona reports on the recently funded European Union Tissue Engineering project in more detail than other news sources have. fona’s information comes from CORDIS (Community Research & Development Information Service) and from a press release from the University of Liverpool.

The stem cell project is being lead by the University of Liverpool and the Italian pharmaceutical company Fidia. Tissue Engineering, which is a collection of technologies whose goal is the regeneration of tissues and organs, has included many different components that have not been put together. One of the goals of this project, known as STEPS (Systems Approach to Tissue Engineering Processes and Products), is to “systematically link together all aspects of this multi-disciplinary process by applying the logistics of systems engineering.” According to the fona article, The technological components will include cell sourcing and manipulation, novel biomaterial development, bioreactor design and the integration of TE constructs into the living host. Moreover, the programme incorporates an analysis of the socio-economic issues related to ethics and health economics. This will include an assessment of the public acceptability of these emerging technologies and the ability of private and public health insurance systems to pay for it.” The research project, in other words, will be considering socio-economic issues as well as technological and scientific issues.

Most of the research will be done on adult stem cells rather than embryonic stem cells, and the goal is to have cost-effective, clinically viable tissue engineering within 4 years.

More on Hearts and Bone Marrow Stem Cells

More on Hearts and Bone Marrow Stem Cells

The Telegraph in Calcutta reported on September 20 on a study performed at the All India Institute of Medical Sciences in New Delhi. The institute director said that 35 patients who had heart attacks and 17 with heart failure had been treated with stem cells from their own bone marrow. 8 of the 17 heart failure patients showed improved heart function, while 20 patients who did not receive stem cells did not show improvement. The heart attack patients also showed improvement, but the article does not give details.

Other Indian scientists have said that the study was designed in such a way that the results could not be attributed to the stem cells, and that it should have been conducted in a blinded manner by independent researchers rather than the treaters.